Outcome in Adult Eisenmenger Syndrome Patients
Study Questions:
What are predictors for death in adults with Eisenmenger syndrome (ES)?

Methods:
A retrospective review of patients >16 years old followed at 11 international adult congenital heart disease (ACHD) clinics was performed. Patients were categorized as having pretricuspid lesions, post-tricuspid lesions, and mixed lesions (combined pre- and post-tricuspid lesions). Data examined included clinical status, oxygen saturation, electrocardiography, transthoracic echocardiography (including tricuspid annular plane systolic excursion [TAPSE]) and presence or absence of pericardial effusion, 6-minute walk, albumin, sodium, B-type natriuretic peptide (BNP), and C-reactive protein (CRP). Survival was calculated using the Kaplan-Meier method, and both univariable and multivariable Cox regression analyses were performed.

Results:
A total of 1,098 patients were studied. The median age was 34.4 years (range 16.1-84.4 years), 65.1% of patients were female, and 31.9% had Down syndrome. The majority of patients had post-tricuspid lesions (n = 643, 58.6%), followed by those with complex lesions (n = 315, 28.7%) and pretricuspid lesions (n = 140, 12.8%)....

http://www.acc.org/latest-in-cardiology/journal-scans/2016/12/20/13/46/predictors-of-death-in-contemporary-adult-patients
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