Outcomes After Corneal Crosslinking for Keratoconus in Child
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The aim of this study was to assess the effect of corneal crosslinking on vision and keratometry in children and young adults with progressive keratoconus.

A retrospective medical history examination of keratoconus patients aged 22 or younger who underwent corneal crosslinking was carried out. The logarithm of corrected distance visual acuity (CDVA); keratometry, including maximum keratometry (Kmax); pachymetry; and complete wavefront aberration were among the outcome tests. At the beginning of the study, as well as at 12 and 24 months after surgery, measurements were taken.

Results:
--57 eyes of 49 patients aged 12 to 22 years were assessed.

--The mean preoperative CDVA was logarithm of the Minimum Angle of Resolution 0.38 ± 0.32 (20/48), with a mean postoperative CDVA of 0.29 ± 0.31 (20/39) and 0.31 ± 0.31 (20/41) at 12 and 24 months postoperatively, respectively.

--Compared with preoperative mean Kmax, there was an improvement of -0.8 diopters (D) to a mean postoperative Kmax of 59.1 ± 9.1 D at 12 months and 1.3 D to 59.7 ± 8.8 D at 24 months.

--Subanalysis excluding the second eye of patients who underwent bilateral crosslinking showed similar results. Linear mixed modeling showed significant improvement in Kmax at both 12 and 24 months postoperatively.

--Minimum central corneal thickness initially decreased but stabilized at 24 months after crosslinking. Total wavefront aberration remained stable.

To summarize, corneal crosslinking stabilizes, and in certain cases increases, visual and corneal parameters in keratoconus patients in children and young adults. The procedure is safe and well-tolerated, and it can help young patients avoid keratoconus progression.

Source: https://journals.lww.com/corneajrnl/Abstract/9000/Outcomes_After_Corneal_Crosslinking_for.95771.aspx
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