Outcomes of Conductive Keratoplasty Combined with Corneal Cr
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A Study was conducted to assess the effectiveness of a novel treatment for patients with advanced corneal ectasia and loss of visual acuity (VA). Conductive keratoplasty (CK) is performed to improve VA followed by epithelium-on (epi-on) corneal crosslinking (CXL) to stabilize the cornea after CK.

Patients with keratoconus or postsurgical ectasia and best spectacle-corrected distance VA (CDVA) less than 20/40 were included. Conductive keratoplasty was performed followed a day later by epi-on CXL. Measures included uncorrected distance visual acuity (UDVA) and CDVA, as well as refractive and tomographic measures and tomographic indices.

Results:
--Data from 50 eyes of 45 patients were analyzed. Mean follow-up was 15.1 ± 12.2 months (range: 2 to 51). Overall, UDVA and CDVA improved postoperatively.

--Subjective refraction and tomographic metrics did not show consistent changes, but changes in tomographic indices were associated with treatment follow-up time.

--At the 1-year visit, mean UDVA significantly improved over baseline by approximately 3 lines; mean CDVA improved significantly by approximately 2 lines. No eye lost lines of CDVA.

--Change in the Index of Surface Variance (ISV) was associated with treatment, and the D-Index trended over follow-up time.

Finally, in patients with advanced ectasia, conductive keratoplasty combined with a patented epi-on CXL therapy enhanced vision. This CK/epi-on CXL therapy has the potential to improve VA in patients with ectasia-related vision loss.

Source: https://www.dovepress.com/outcomes-of-conductive-keratoplasty-combined-with-corneal-crosslinking-peer-reviewed-article-OPTH
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