Ovarian sertoli-leydig cell tumor in a 16-year-old: case rep
Published in the Case Reports in Obstetrics and Gynecology, the authors report a case of primary poorly differentiated ovarian Sertoli-Leydig cell tumor (SLCT) involving the left ovary in a 16-year-old single woman who presented with a 3-month history of a pelviabdominal mass, acne, hirsutism, and menstrual irregularities.

A 16-year-old single woman presented with a 3-month history of a pelvi-abdominal mass, acne, hirsutism, and menstrual irregularities. Systemic review was remarkable for decreased appetite, shortness of breath, and constipation. Physical examination revealed acne, hirsutism, abdominal swelling, and a diffuse, tender, and palpable mass extending from lower pelvis/abdomen to umbilicus.

Laboratory tests showed increased total serum levels of testosterone (T) of 7.8 ng/mL (normal range: 0.2–0.7 ng/mL), dehydroepiandrosterone (DHEA) of 7.2 ng/mL (normal range: 0.8–3.2 ng/mL), and CA-125 of 272 U/mL (normal range <35 U/mL). All other laboratory tests including complete blood count (CBC), renal, bone, hepatic and coagulation profiles, alkaline phosphatase, carcino-embryonic antigen (CEA), alfa-feto protein (AFP), CA 15-3, CA 19-9, estradiol (17β-estradiol), luteinizing hormone (LH), follicle-stimulating hormone (FSH), sex hormone-binding globulin (SHBG), adrenocorticotropic hormone (ACTH), prolactin, and cortisol levels were within normal ranges.

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