PF in an 11-Year-Old Mexican Girl with Response to Oral Daps
Now open: Certificate Course in Management of Covid-19 by Govt. Of Gujarat and PlexusMDKnow more...Now open: Certificate Course in Management of Covid-19 by Govt. Of Gujarat and PlexusMDKnow more...
Introduction
Pemphigus foliaceus (PF) is an autoimmune, blistering skin disease, targeting desmoglein-1. There are two major categories: the endemic form is common in children in rural areas of Brazil where the bite of the black fly Simulium nigrimanum is thought to be the mode of transmission of the disease [1]. However, the sporadic form is rare in children, with less than 40 cases documented in the literature. Because of the rarity of the disease, evidence on the treatment and prognosis in children is lacking. We describe a girl with sporadic PF who responded well to dapsone.

Case Report
An 11-year-old Mexican girl presented with a six-month history of an asymptomatic generalized skin eruption involving the face, trunk, and extremities. The condition initially began as tense blisters on the face, which spontaneously resolved leaving erythema and scaling. She was treated with topical corticosteroids and systemic antibiotics without improvement. The lesions progressed slowly, eventually covering her entire skin surface, accompanied by general malaise, chills, and edema of the lower extremities. On physical examination, she had scaling erythroderma with yellow-greenish crusts involving her entire body surface.....

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3876713/
Like
Comment
Share