Pancreatic adenocarcinoma with atypical metastases to the br
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Pancreatic adenocarcinoma is the most common exocrine pancreatic cancer and has a five-year survival rate of 5–7%. Adenocarcinomas of the pancreas most commonly spread to the liver, followed by lung and bone metastases. Central nervous system involvement is exceedingly rare and has been reported to be less than 1%.We report the first case of pancreatic adenocarcinoma metastatic to the brainstem and review predisposing factors and treatment options. The patient we describe was a 63-year-old found to have stage IIb pancreatic cancer. He underwent an uncomplicated pancreaticoduodenectomy followed by standard chemoradiation then adjuvant 5FU and gemcitabine chemotherapy along with a vaccine therapy. After two years, the patient had isolated recurrences in lung and adrenal gland with excellent responses to ablative therapies. He ultimately developed brain stem metastases after five years and these were treated with Gamma Knife therapy and bevacizumab....

http://www.edoriumjournals.com/journal-of-case-reports-and-images-in-oncology/archive/2016-archive/100020Z10PD2016-dillon/100020Z10PD2016-dillon-full-text.php
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