Patients with mitral annulus calcification at higher risk of
A retrospective review of more than 24,000 patients who underwent an echocardiogram at Mayo Clinic finds that nearly one-quarter of the patients had mitral annulus calcification, a chronic degeneration of tissue at the base of the heart's mitral valve. Mitral valve dysfunction was more than twice as prevalent for those patients, who also were at higher risk of all-cause mortality.

Mitral annulus calcification has been associated with cardiovascular diseases and events, as well as higher mortality rates, though less is known about its associations with ventricular and valvular function. The new Mayo Clinic research suggests that mitral annulus calcification is a predictor of mortality, as well as a marker of valvular and cardiovascular disease.

Among key findings:
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Moderate or greater degrees of mitral valve dysfunction was more than twice as common in patients with mitral annulus calcification than without.
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After adjustment for comorbidities, mitral annulus calcification was associated with higher mortality.
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Mortality was highest in patients with mitral annulus calcification and mitral valve dysfunction.

Source: https://newsnetwork.mayoclinic.org/discussion/patients-with-mitral-annulus-calcification-at-higher-risk-of-heart-valve-and-cardiovascular-disease-mayo-clinic-research-finds/
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