Pediatric Lung Imaging Features of COVID-19: A Systematic Re
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Pediatric COVID-19 studies have been mostly restricted to case reports and small case series, which have prevented the identification of specific pediatric lung disease patterns in COVID-19. The overarching goal of this systematic review and meta-analysis is to provide the first comprehensive summary of the findings of published studies thus far describing COVID-19 lung imaging data in the pediatric population.

A systematic literature search of PubMed was performed to identify studies assessing lung-imaging features of COVID-19 pediatric patients (0-18 years). A total of 29 articles (n=1026 children) based on chest CT images were included.

The main results of this comprehensive analysis are as follows:

-- Over a third of pediatric patients with COVID-19 had normal chest CT scans and only 27.7% had bilateral lesions
-- The most typical pediatric chest CT findings of COVID-19 were ground-glass opacities (GGO) and the presence of consolidations or pneumonic infiltrates
-- The lung imaging findings in children with COVID-19 were overall less frequent and less severe than in adult patients; and
-- Typical lung imaging features of viral respiratory infections in the pediatric population such as increased perihilar markings and hyperinflation were not reported in children with COVID-19.

Conclusively, Chest CT manifestations in children with COVID-19 could potentially be used for early identification and prompt intervention in the pediatric population.