Perinatal outcomes of high dose versus low dose oxytocin reg
Researchers compared perinatal outcomes among pregnant mothers who received the two different oxytocin regimens and identified risk factors associated with adverse perinatal outcomes.

A facility-based comparative cross-sectional study was conducted with 216 pregnant women who received high and low-dose oxytocin for labor induction. Socio-demographics, reproductive characteristics of mothers, and perinatal outcomes data were collected. Chi-square test and logistic regression were done to see the effect of different oxytocin regimens on perinatal outcomes.

- Higher adverse perinatal outcomes and higher non-reassuring fetal heart rate pattern was observed among mothers who received high dose oxytocin compared to mothers who received low dose oxytocin.

- Using high oxytocin dose, cesarean birth, instrumental birth, and antepartum hemorrhage were risk factors of adverse perinatal outcomes.

Using high dose oxytocin, antepartum hemorrhage, cesarean birth, and instrumental birth was associated with increased risk of adverse perinatal outcomes. They recommend using low-dose oxytocin for better perinatal outcomes.

BMC Pregnancy and Childbirth
Source: https://doi.org/10.1186/s12884-021-04052-5
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