Peripapillary Choroidal Vascular Characteristics in Papilled
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Choroidal vascularity index measured by image binarization method from peripapillary optical coherence tomography sections has been found significantly lower in papilledema patients than healthy controls. The purpose of this study was to compare peripapillary choroidal parameters in papilledema patients with control subjects.

Peripapillary spectral domain optical coherence tomography scans of 34 patients with papilledema and 34 healthy controls are acquired for the study. Images are binarized with the ImageJ software to calculate total choroidal area, stromal area, luminal area, and choroidal vascularity index.

Results:
--Total choroidal area, luminal area, and choroidal vascularity were significantly lower in papilledema patients compared with healthy controls on right: (1.343 ± 0.286 vs. 1.694 ± 0.344, ; 0.880 ± 0.209 vs. 1.167 ± 0.255; 65.28 ± 2.99% vs. 68.68 ± 2.81%, respectively) and
left eyes: (1.376 ± 0.308 vs. 1.647 ± 0.339; 0.899 ± 0.231 vs. 1.134 ± 0.237; 64.92 ± 3.44 vs. 68.84 ± 3.23, respectively).

--No difference was found between active and remitted stages of papilledema in terms of choroidal parameters.

Finally, papilledema patients have substantially decreased peripapillary total choroidal region, luminal area, and choroidal vascularity index. These parameters may be useful for quantitatively assessing choroidal vascularity in papilledema and differentiating between different types of optic disc edema.

Source: https://journals.lww.com/optvissci/Abstract/2021/04000/Analysis_of_the_Peripapillary_Choroidal_Vascular.3.aspx
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