Personal use of permanent hair dye not associated with great
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Women who use permanent hair dye products to color their hair at home do not experience greater risk of most cancers or greater cancer related mortality, finds a study published by The BMJ today.

In a prospective cohort study, 117200 women who were free of cancer at baseline, reported information on personal use of permanent hair dyes, and were followed for 36 years.

-- Ever users of permanent hair dyes had no significant increases in risk of solid cancers or hematopoietic cancers overall compared with non-users.
-- Additionally, ever users did not have an increased risk of most specific cancers (cutaneous squamous cell carcinoma, bladder cancer, melanoma, estrogen receptor positive breast cancer, progesterone receptor positive breast cancer, hormone receptor positive breast cancer, brain cancer, colorectal cancer, kidney cancer, lung cancer, and most of the major subclasses and histological subtypes of hematopoietic cancer) or cancer related death.
-- Basal cell carcinoma risk was slightly increased for ever users.
-- Cumulative dose was positively associated with risk of estrogen receptor negative breast cancer, progesterone receptor negative breast cancer, hormone receptor negative breast cancer, and ovarian cancer.
-- An increased risk of Hodgkin lymphoma was observed only for women with naturally dark hair, and a higher risk of basal cell carcinoma was observed for women with naturally light hair.

Conclusively, No positive association was found between personal use of permanent hair dye and risk of most cancers and cancer related mortality. The increased risk of basal cell carcinoma, breast cancer (estrogen receptor negative, progesterone receptor negative, hormone receptor negative) and ovarian cancer, and the mixed findings in analyses stratified by natural hair color warrant further investigation.

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