Pfizer-BioNTech Vaccine Appears Effective Against Mutation I
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Pfizer Inc. and BioNTech’s COVID-19 vaccine appeared to work against a key mutation in the highly transmissible new variants of the coronavirus discovered in the U.K. and South Africa, according to a laboratory study.

The not-yet peer reviewed study by Pfizer and scientists from the University of Texas Medical Branch indicated the vaccine was effective in neutralising virus with the so-called N501Y mutation of the spike protein.

The mutation could be responsible for greater transmissibility and there had been concern it could also make the virus escape antibody neutralisation elicited by the vaccine, said Phil Dormitzer, one of Pfizer’s top viral vaccine scientists.

The study was conducted on blood taken from people who had been given the vaccine. Its findings are limited, because it does not look at the full set of mutations found in either of the new variants of the rapidly spreading virus. Dormitzer said it was encouraging that the vaccine appears effective against the mutation, as well as 15 other mutations the company has previously tested against.

The Pfizer/BioNTech vaccine and the one from Moderna Inc., can be quickly tweaked to address new mutations of a virus if necessary. Scientists have suggested the changes could be made in as little as six weeks.

Source:
https://www.thehindu.com/sci-tech/health/pfizer-and-biontech-vaccine-appears-effective-against-mutation-in-new-coronavirus-variants-study/article33526846.ece#
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