Pfizer, Moderna Vaccines 'Don't Appear To Pose Serious Risk'
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The mRNA Covid-19 vaccines by Pfizer/BioNTech and Moderna do not appear to pose any serious risk during pregnancy, according to new data. The study, along with existing research showing mRNA vaccines are effective in pregnant and lactating women, suggests that the benefits of the vaccines outweigh the risks.

The team reviewed data on 35,691 pregnant people between December 14, 2020, to February 28, 2021, from the CDC's V-safe smartphone-based surveillance system, as well as data from the CDC's Vaccine Adverse Event Reporting System. All participants were pregnant and were between 16 to 54 years old.

The researchers followed a group within the V-safe system to gather more data on pregnancy outcomes and complications. This registry included 3,958 pregnant participants who had received an mRNA vaccine. The researchers found 827 completed pregnancies, and 115 experienced a pregnancy loss, while 712 resulted in a live birth.

Preterm births occurred in 9.4 percent of participants and only 3.2 percent of these births were of small gestational age. There were no neonatal deaths reported. There were 221 pregnancy-related adverse events reported to the CDC's VAERS registry, and 46 of them were miscarriages.

"Although not directly comparable, calculated proportions of adverse pregnancy and neonatal outcomes in persons vaccinated against Covid-19 who had a completed pregnancy were similar to incidences reported in studies involving pregnant women that were conducted before the Covid-19 pandemic," the results of the study read.

The study also looked at vaccine side effects during pregnancy. Researchers found the most common side effect from the vaccine was pain at the injection site, which appeared to occur more frequently in vaccine recipients who were pregnant. However, headaches, muscle aches, chills and fever were reported less frequently by pregnant people.

Source:
https://www.nejm.org/doi/full/10.1056/NEJMoa2104983?query=featured_home
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