Photophobia Associated with Traumatic Brain Injury, finds S
This study reports the prevalence and relative risk of photophobia in patients with traumatic brain injury (TBI). This study aimed to conduct a systematic review and meta-analysis to determine the prevalence and relative risk of photophobia in patients with TBI.

Publications reporting the prevalence of photophobia after TBI in patients of any age were included. A series of meta-regression analyses based on a generalized linear mixed model was performed to identify potential sources of heterogeneity in the prevalence estimates.

--75 eligible publications were identified. The prevalence of photophobia was 30.46% at 1 week after the injury.

--Prevalence decreased to 19.34% between 1 week and 1 month after TBI and to 13.51% between 1 and 3 months after the injury.

--The rapid decrease in the prevalence of photophobia in the first 3 months after a TBI injury was significant.

--3 months post-TBI, the prevalence of photophobia leveled off to a near plateau with nonsignificant variability, increasing between 3 and 6 months and decreasing between 6 and 12 months since TBI.

--Subgroup analysis of 14 publications that contained control data showed that the estimated risk ratio for photophobia was significantly higher in the TBI than in the control group during the entire 12 months after TBI.

Conclusively, this study shows that photophobia is a common complaint following a TBI, and that it mainly fades for many people within three months of the injury. Photophobia, on the other hand, can continue up to a year in some people, and probably longer.