Pioneering Staged Gamma Knife Therapy for Large Brain Metast
The challenge of large tumors:

Brain metastases arise in some 20 to 40 percent of patients diagnosed with systemic cancer, and that proportion is likely to rise with earlier detection and personalized targeted therapies that lengthen survival for increasing numbers of oncology patients.

Meanwhile, in recent years Gamma Knife radiosurgery has gained favor as monotherapy for brain metastases. It is minimally invasive, is performed on an outpatient basis, results in little or no disruption of systemic treatment for the patient’s primary cancer, and is often highly effective in controlling brain tumors while avoiding the toxicity of whole-brain radiation therapy....

https://consultqd.clevelandclinic.org/2016/12/pioneering-staged-gamma-knife-therapy-large-brain-metastases/
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