Platelet-rich plasma injections preffered over Corticosteroi
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The role of corticosteroids and platelet-rich plasma (PRP) in the treatment of rotator cuff tendinopathies has been the subject of conflicting research. The structural and clinical changes in RC muscles after corticosteroids and PRP injections were compared.

All individuals with diagnosis of RC tendinitis were considered. Individuals were randomly allocated to either receive PRP or corticosteroids. Overall, 3cc of PRP was injected within the subacromial joint and another 3cc was injected at the site of the tendon tear, under the guide of sonography. For the corticosteroid group, 1cc of Depo-medrol 40mg and 1cc of lidocaine (2%) was injected within the subacromial joint.

Results:
--Overall, 58 patients entered the study. Comparison of pain, range of motion (ROM), Western Ontario RC (WORC), Disability of Arm-Hand-Shoulder (DASH) scores, and supraspinatus thickness showed significant improvement during follow-ups in both groups.

--During 3 months of follow-up, pain improvement was significantly better within the PRP group.

--Regarding ROM, the PRP group had significant improvement in adduction and external rotation compared to the corticosteroid group.

Finally, it was discovered that PRP produces similar results to corticosteroids in most clinical aspects among patients with RC tendinopathies; however, pain and range of motion can improve more significantly with PRP use. Since corticosteroids can be contraindicated in certain patients and are linked to the risk of tendon rupture, researchers recommend that patients with RC tendinopathy use PRP instead of corticosteroid-based injections.

Source: https://josr-online.biomedcentral.com/articles/10.1186/s13018-021-02470-x
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