Post-transplant lymphoproliferative disease of the larynx
Laryngeal post-transplant lymphoproliferative disease (PTLD) is rare. Here, Journal of Surgical Case Reports, Volume 2019, Issue 4, April 2019, rjz111 describes two pediatric cases.

The first, a 15-month-old who underwent liver transplantation at 5 weeks, presented with airway distress. Airway evaluation identified epiglottic and arytenoid infiltrate, and biopsy was consistent with polymorphic PTLD.

The second, a 23-month-old who underwent liver transplantation at 13 months, presented with progressive stridor. Airway evaluation revealed sub-mucosal infiltrate of the epiglottis, arytenoids, post-cricoid region, and uvula. Biopsy was consistent with monomorphic PTLD. Airway findings and symptoms resolved for both after immunosuppression reduction. PTLD diagnosis requires a high index of suspicion in post-transplant patients with airway obstruction.

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