Postoperative Complications in Patients With Hereditary Hemo
The purpose of this study is to determine differences in the rates of 90-day postoperative complications and 2 and 5 year surgical outcomes between patients with and without hereditary hemochromatosis (HH) after total joint arthroplasty (TJA).

Patients with a history of HH were identified within the THA and TKA cohorts and matched with non-HH patients based on age, sex, Charlson Comorbidity Index, smoking status, and obesity. 90 day medical complications assessed included renal failure, arrhythmia, bleeding complications, blood transfusion, pneumonia, stroke, deep vein thrombosis, liver failure, heart failure, pulmonary embolism, sepsis, surgical site infection, wound dehiscence, readmission rate, and death. 2 and 5 year surgical complications assessed included all-cause revision, prosthetic joint infection, implant loosening, joint stiffness, and manipulation under anesthesia.

--Compared with non-HH patients, patients with HH had higher rates of stiffness at 2 and 5 years after THA as well as higher rates of aseptic loosening at 5 years after TKA.

--However, patients with HH undergoing THA and TKA had no notable difference in 90-day postoperative complications when compared with non-HH patients.

Conclusively, patients with HH who underwent TJA had worse 2 and 5 year surgical outcomes than non-HH patients, with no greater risk of 90-day medical problems. These findings could help surgeons make surgical decisions for patients with HH who are having TJA.