Prediabetes May Be an Independent Risk Factor for MI
Even prediabetes seemed to spell bad news for heart health. Prediabetes -- defined as an Hba1c between 5.7% to 6.4% -- among hospitalized patients was associated with 41% higher odds for myocardial infarction (MI, OR 1.41, 95% CI 1.35-1.47). And in a model adjusted for multiple factors including age, sex, race, family history of MI, dyslipidemia, hypertension, diabetes, nicotine dependence, and obesity status, presence of prediabetes was still significantly associated with a higher chance of experiencing MI (OR 1.25, 95% CI 1.20-1.31).

Prediabetes stood as an independent risk factor for myocardial infarction, despite adjusting for all the well-established risk factors. The study findings would also reinforce the importance of early recognition through screening and early intervention to aggressively manage the cardiovascular risk factors to prevent myocardial infarction.