Prediction model of renal function recovery for primary memb
The clinical and pathological impact factors for renal function recovery in acute kidney injury (AKI) on the progression of renal function in primary membranous nephropathy (PMN) with AKI patients. Renal function recovery was found in 72 of 124 (58.1%) patients and 41 of 72 (56.9%) patients in the derivation and validation cohorts, respectively. The prognostic nomogram model included determinants of sex, age, the comorbidity of hypertensive nephropathy, the stage of the glomerular basement membrane, and diuretic treatment with a reasonable concordance index of 0.773 (95%CI,0.716–0.830) in the derivation cohort and 0.773 (95%CI, 0.693–0.853) in the validation cohort. Diuretic use was a significant impact factor with a decrease in renal function recovery in PMN with AKI patients. The predictive nomogram model provides a useful prognostic tool for renal function recovery in PMN patients with AKI.

Source: https://bmcnephrol.biomedcentral.com/articles/10.1186/s12882-022-02882-9
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