Prediction of postinfectious bronchiolitis obliterans progno
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The prognosis of postinfectious bronchiolitis obliterans (PIBO) has many implications, ranging between reduced quality of life and life-threatening complications. Researchers evaluated the prognostic factors for PIBO using the baseline clinical characteristics of patients and built a prediction model for determining the prognoses of PIBO patients using the identified parameters.

Researchers included 47 PIBO patients who underwent spirometry and impulse oscillometry and followed them up for at least 1 year. A patient's prognosis was classified as poor if the patient experienced at least one of the following: persistent respiratory symptoms for more than 1 year, two or more instances of hospitalizations due to respiratory symptoms, or more than one intensive care unit admission.

Results:
--The prognosis of 32/47 patients was good, while that of 15/47 was poor.

--Spirometry results showed significantly lower forced vital capacity (FVC), forced expiratory volume in the first second (FEV1), forced expiratory flow at 25%–75% of FVC, and post-bronchodilator (BD) FEV1 values in the poor prognosis group; chest computed tomography (CT) demonstrated more inflammatory bronchiolitis findings.

--A nomogram was created for predicting prognoses using post-BD FEV1 and inflammatory bronchiolitis on chest CT. The area under the curve for the nomogram was 84.6%.

In conclusion, PIBO patients with poor prognosis have lower pulmonary function values and more inflammatory bronchiolitis findings on initial review. The PIBO prognosis nomogram is easy to use and can be applied at the time of diagnosis.

Source: https://onlinelibrary.wiley.com/doi/10.1002/ppul.25220?af=R
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