Predictive risk factors for postoperative pneumonia after he
Released: Doctor's guide to managing the Coronavirus/COVID19 outbreakWatch VideoDownload SlidesReleased: Doctor's guide to managing the Coronavirus/COVID19 outbreakWatch VideoDownload Slides
According to a study published in BMC Anesthesiology , pneumonia is a frequent complication in patients undergoing heart transplantation (HTx) that increases morbidity and mortality in this population. Nevertheless, the risk factors for postoperative pneumonia (POP) are still unknown. The aim of this study was to investigate the predictive risk factors for POP in HTx recipients.

In this study, all patients undergoing HTx were included. All cases of POP occurring until hospital discharge were investigated. The study aimed to determine risk factors using univariate and multivariate Cox regression models.

A total of 175 patients were included without any patients being lost to follow-up, and 89 instances of POP were diagnosed in 59 (34%) patients. Enterobacteriaceae and Pseudomonas aeruginosa were the most common pathogens. In the multivariate analysis, the risk factors were preoperative mechanical ventilation and perioperative blood transfusion. POP significantly impacted mortality at 30 days and 1 year and was associated with a longer duration of mechanical ventilation, time to weaning from venoarterial extracorporeal membrane oxygenation and stay in an intensive care unit. Plasma exchanges and intravenous administration of immunoglobulins did not increase the risk of POP.

In conclusion, After HTx, preoperative mechanical ventilation and blood transfusion were risk factors for POP and were associated with increased mortality. Enterobacteriaceae and Pseudomonas aeruginosa are the most common pathogens of POP.

Source : https://bmcanesthesiol.biomedcentral.com/articles/10.1186/s12871-019-0923-3
Like
Comment
Share
Dr. V●●●●●●j D●●●i
Dr. V●●●●●●j D●●●i Legal Medicine
Only 1 comment with due regard : Before trying to link blood transfusion with postop pneumonia, it will be worthwhile to know that blood transfusion by itself, per se, may not be a contributing factor; the factor is very often the cause for which blood transfusion was necessary. This may be verified.
Mar 4, 2020Like