Prenatal management and perinatal outcome in giant placental
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Abstract

Background
Giant placental chorioangiomas have been associated with a number of severe fetal complications and high perinatal mortality.

Case presentation
We report a case of giant chorioangioma with fetal hydrops, additionally complicated by severe anemia, mild cardiomegaly with hyperdinamic heart circulation and maternal mirror syndrome. Intrauterine blood transfusion and amniodrainage was performed at 29?weeks. Worsening of the fetal and maternal condition prompted us to proceed with delivery at 29?+?5?weeks. The newborn died 3 hours later due to pulmonary hypoplasia and hemodynamic failure. Maternal course was favourable, mirror syndrome resolved in the second day and the patient was discharged four days following delivery.

Conclusions
In the case described here, fetal condition got worse despite of the anemia correction and amniodrainage. Our outcome raises the issue whether additional intrauterine clinical intervention, as intersticial laser, should have been performed to stop further deterioration of the fetal condition when progressive severe hydrops develops....

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3565867/
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