Preterm Meconium Stained Amniotic Fluid is an Independent Ri
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To investigate the association of maternal peripartum bacteremia and meconium stained amniotic fluid in early preterm deliveries a study was conducted. Researchers conducted a single-center retrospective study, in a tertiary university-affiliated medical center. The study cohort included women with culture-proven maternal bacteremia who had a preterm delivery between 24 to 34 weeks of gestation. The control group composed of women of similar gestational age at delivery without bacteremia. Maternal characteristics were compared between the groups.

During the six-years study period, there were 86,590 deliveries in our center. 2625 (3.03%) women had early preterm deliveries (24-34 weeks), of the 22 (0.84%) were diagnosed with peripartum bacteremia. The groups were similar with regard to obstetric and demographic characteristics. In the peripartum maternal bacteremia group, researchers found significantly higher rates of meconium-stained amniotic fluid. Logistic regression of multivariable analysis demonstrated that meconium-stained amniotic fluid is an independent risk factor for maternal bacteremia adjusted for gestational age, intrapartum fever, and leukocytosis

Preterm meconium-stained amniotic fluid is an independent risk factor for maternal bacteremia among women with early preterm delivery. More studies are needed to determine the need for broad-spectrum antibiotic prophylaxis therapy in preterm deliveries complicated by meconium-stained amniotic fluid.

Source:https://www.ejog.org/article/S0301-2115(20)30846-0/fulltext?rss=yes
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