Prevalence and Long-Term Outcomes of Solid Organ Transplant
Now open: Certificate Course in Management of Covid-19 by Govt. Of Gujarat and PlexusMDKnow more...Now open: Certificate Course in Management of Covid-19 by Govt. Of Gujarat and PlexusMDKnow more...
A Study was conducted to describe the prevalence and long-term outcomes of kidney, liver, and heart transplant for children with intellectual disability.

A retrospective cohort study of children who received their first kidney, liver, or heart transplant was conducted. The recipients with a definite intellectual disability were compared to those with a possible or no intellectual disability. For both graft and patient survival, Kaplan-Meier survival estimates were determined. The correlation between ID and graft and patient survival was calculated using Cox proportional hazard models.

Results:
--Over the study period, children with definite ID accounted for 594 of 6747 first pediatric kidney-alone, 318 of 4566 first pediatric liver-alone, and 324 of 3722 first pediatric heart-alone transplant recipients.

--ID was not significantly associated with patient or graft survival among liver and heart transplant recipients.

--Among kidney transplant recipients, definite ID was significantly associated with higher graft survival and lower patient survival, but absolute differences were small.

Conclusively, Children with ID account for 7-9% pediatric transplant recipients with comparable long-term outcomes to other pediatric recipients. These findings provide important empirical support for policies that include children with ID as transplant candidates.

Source: https://www.jpeds.com/article/S0022-3476(21)00305-X/fulltext?rss=yes
Like
Comment
Share