Primary CNS vasculitis masquerading as Glioblastoma
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Isolated angitis of the central nervous system (IACNS)/primary angitis of central nervous system (PACNS) represents a rare and poorly understood form of vascular inflammatory disease restricted to the brain and spinal cord.Delay in diagnosis due to focal nature of the lesion also contributes to the poor prognosis as the dismal natural history and immunosuppressive therapy. Histopathology usually reveals granulomatous inflammation affecting arterioles and small arteries of the parenchyma or leptomeninges. Nonspecific clinical manifestations and various imaging findings often lead to an incorrect or delayed diagnosis and treatment, particularly for an extremely rare form of tumor-like lesion.To date, only a few cases with tumor-like isolated angitis of CNS have been reported with clear and definitive diagnostic workup. We herein present a case of IACNS presenting as a mass lesion and raised intracranial tension.

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