Primary Pulmonary Synovial Sarcoma in Pregnancy
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Introduction
Soft-tissue synovial sarcomas commonly arise in paraarticular locations of the extremities but are rarely found in the lungs. Primary pulmonary synovial sarcoma is an aggressive tumor accounting for approximately 0.05% of all primary lung malignancies. The most common presenting symptoms include chest pain, cough, dyspnea, and hemoptysis. Diagnosis is made by a combination of radiologic imaging, histologic analysis, and cytogenetic testing. The recent identification of a chromosomal translocation specific to pleuropulmonary synovial sarcoma has increased the recognition of this particular sarcoma subtype. The chromosomal translocation t(x;18) is present in more than 80% of cases of primary pulmonary synovial sarcoma. The mainstays of treatment are surgical resection followed by radiation or chemotherapy.

Case Presentation
A 38-year-old African American woman at 26 weeks' gestation presented with a 3-week history of dyspnea, upper right back pain, and orthopnea. Her pregnancy was complicated by the finding of a small fetal ventricular septal defect on ultrasound. The remainder of her medical history was noncontributory. Physical examination revealed a patient in moderate distress with a heart rate of 126, blood pressure 140/68, and respiratory rate of 25. Auscultation was notable for crackles in the base of the right lung. Chest roentgenography demonstrated complete opacification of the right lower lobe with an adjacent effusion....

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502773/
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