Prominent Skin Markings: A New Reason to Suspect Melanoma
Now open: Certificate Course in Management of Covid-19 by Govt. Of Gujarat and PlexusMDKnow more...Now open: Certificate Course in Management of Covid-19 by Govt. Of Gujarat and PlexusMDKnow more...
A 64-year-old woman with severe actinic damage presented with a pigmented lesion of recent onset on the external aspect of her left leg. The clinical examination showed an irregular pigmented macule with a lentiginous appearance and measuring 7 mm at its widest point; the surrounding skin showed signs of severe sun damage, with multiple solar lentigines.

Polarized light dermoscopy showed a discrete irregular pigment network, light-brown structureless areas, hypopigmented areas, and sparse, irregularly distributed, dots. One particularly remarkable finding was the presence of prominent skin markings in the form of intersecting lines that were paler in color than the rest of the lesion and interrupted other structures. Also visible were dotted vessels in the hypopigmented areas that were more visible than those in the surrounding skin.

Considering the clinical context (a flat pigmented lesion of recent onset in a patient with severely sun-damaged skin) and the dermoscopic findings, the lesion was excised. The histopathologic diagnosis was melanoma in situ with a lentiginous growth pattern.

The dermoscopic finding of prominent skin markings was recently described as a powerful diagnostic indicator of melanoma in situ versus atypical nevus, particularly in sun-damaged areas of the skin. These markings, which are associated with high levels of interobserver agreement, are intersecting linear furrows, lighter in color than the rest of the lesion. They have been linked in particular to melanoma in situ or melanoma with a low Breslow thickness located on the lower limbs.

In conclusion, prominent skin markings are a new dermoscopic marker that should raise suspicion in melanocytic lesions and could help increase the early detection of melanoma, particularly in sun-damaged skin.

Source: https://www.actasdermo.org/en-prominent-skin-markings-a-new-articulo-S1578219021000858
Like
Comment
Share