Pseudomyxoma peritonei: an incidental finding at cesarean se
The cancers most likely occurring during pregnancy are those of the breast, uterine cervix, ovary, lymphomas and the colorectum, in declining order. Of the colorectal neoplasms, approximately 1% are appendiceal in origin. Some of these tumors arise from mucin-2 expressing goblet cells and in some cases, the appendix may perforate and goblet cells proliferate throughout the abdominal cavity.

Large volumes of mucinous material can rapidly amass within the peritoneum. This is a condition known as pseudomyxoma peritonei (PMP), the approach to which was largely palliative until recently.

The following case has been reported in the Journal of Clinical Gynecology and Obstetrics. A 27-year-old nulliparous patient with a presumed dermoid cyst and pelvic pain related to pregnancy was incidentally found to have disseminated PMP during cesarean section at term for a breech presentation.

The patient underwent surgical cytoreduction, operative heated intraperitoneal chemotherapy and early postoperative intraperitoneal chemotherapy, a novel approach known as “the Sugarbaker technique”.

A literature review of this rare clinical scenario and a discussion of diagnosis and management are presented.

Read in detail about the case here: