Psoriasis linked to increased risk for lymphomas, keratinocy
According to data published patients with psoriasis carry a slightly increased risk for cancer, particularly keratinocyte cancer and lymphomas.
Epidemiological studies investigating the association between psoriasis or psoriatic arthritis and cancer have reported conflicting results, where some studies report an increased risk of cancer in individuals with psoriasis or psoriatic arthritis and others do not

To analyze the association and risk for cancer among patients with psoriasis or psoriatic arthritis. The researchers also limited their analysis to original, observational cohort studies of adults with psoriasis or PsA, and that reported the incidence or prevalence of cancer among the participants.
Among the 365 studies included for full-text assessment, 112 were included in the final analysis. These 112 studies featured 2,053,932 patients. The primary outcome was cancer.
The researchers observed no increased cancer risk among patients with psoriasis treated with biologic agents. Psoriatic arthritis was not associated with an overall increased risk for cancer.

“Physicians should be aware that individuals with psoriasis have an increased risk of cancers especially lymphomas and keratinocyte cancers,” Loft said. “Notably, some treatments of psoriasis might cause an increased risk of keratinocyte cancers and exacerbations of lymphomas. In addition, obesity, alcohol use, and smoking, which are all associated with cancers, are more prevalent in individuals with psoriasis. Therefore, promoting a healthy lifestyle is important in individuals with psoriasis as this might improve psoriasis and prevent some of the cancers increased in psoriasis.” – by Jason Laday.

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