Pulmonary embolism and disseminated intravascular coagulopat
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30-year-old man normally fit and healthy presented with collapse and palpitation. He was tachycardic with a heart rate of 120 beats/min and hypoxic with oxygen saturation of 85% on arrival. CT pulmonary angiography confirmed extensive bilateral segmental and sub segmental pulmonary emboli with evidence of right heart strain (Panel A). Laboratory data revealed an elevated international normalized ratio (INR) of 1.4, prolonged partial thrombo plastin time (aPTT) of 49 seconds and a low fibrinogen level of 1.0g/L.

Heparin was administered in view of his coagulopathy. Again, his coagulopathy resolved the following day. Trans oesophageal echocardiography confirmed a large right atrial mass measuring 3.9cm x 1.8cm with a stalk attached near the inferior vena cava (IVC) (Panel B). There was no obstruction to the tricuspid valve. An urgent operation was performed in view of the risk of further pulmonary embolism. On opening the right atrium a large tumour was found (Panel C). It was attached by a stalk to the eustachian valve and was very close to the IVC cannula. There were no other clots or tumour seen in the right atrium or ventricle. The tricuspid valve appeared normal. No myxo matous tumour was identified on H&E stained sections but only abundant partially organised blood clot with degenerate stroma (Panel D). The patient had an uncomplicated recovery and was discharged home on warfarin 6 days after the surgery...

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