Pulmonary tumor thrombotic microangiopathy caused by prostat
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Pulmonary tumor thrombotic microangiopathy (PTTM) is a fatal malignancy-related condition that involves rapidly progressing hypoxia and pulmonary hypertension. We report a case of PTTM caused by prostate carcinoma, which was diagnosed before autopsy in an 81-year-old man. Computed tomography showed diffuse ground-glass opacities, consolidation, and small nodules in the peripheral regions of the lung. Autopsy showed adenocarcinoma cells embolizing small pulmonary arteries with fibrocellular intimal proliferation, which was consistent with PTTM caused by prostate carcinoma.

Case Report
An 81-year-old man (non-smoker) presented with a 3-day history of progressive dyspnea on exertion and palpitation before admission. He had advanced prostate carcinoma and had received androgen-deprivation therapy. Further, he had undergone percutaneous coronary intervention 6 years previously. Prostatic biopsy examination indicated an adenocarcinoma with a Gleason score of 9 (5?+?4). Magnetic resonance imaging (MRI) of the pelvis, abdominal CT, and bone scans showed tumor invasion of the bladder and multiple bone metastases.

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