QOL Improves With Complete Revascularization After STEMI
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Complete revascularization improves angina-related quality of life in patients who have ST-segment elevation myocardial infarction (STEMI) with multivessel coronary artery disease. Both complete revascularization and culprit-lesion-only percutaneous coronary intervention (PCI) improved scores at 6 months on the patient-reported Seattle Angina Questionnaire (SAQ).

The trial enrolled 4041 patients with STEMI and multivessel disease who had undergone successful PCI of the culprit lesion but were found to have nonculprit lesions of at least 70% or a fractional flow reserve measurement of 0.80. Patients were then randomly assigned to complete revascularization of any additional angiographically significant nonculprit lesions or to no further revascularization. Among those allocated to intervention, 122 crossed over to culprit-lesion-only revascularization.

SAQ data were collected at baseline, 6 months, and study end, with final data available from 86.8% of the complete revascularization group and 85.0% of the culprit-only group. Mean age of the study participants was 62 years, 19% were female, and 19% had diabetes. At baseline, 12% of patients reported weekly or daily angina but, importantly, 50% had no self-reported history of angina.

Source: https://www.medscape.com/viewarticle/971869