Quantitative assessment and determinants of the papillary mi
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It is important to track and measure the vessel density of the optic disc using optical coherence tomography angiography (OCTA). The current study looks at the superficial vessel density (VD) of the papillary microvasculature and the factors that influence it.

This was a prospective, cross-sectional study. Superficial VD in healthy individual's optic disc region was measured by OCTA. The factors associated with ocular and systemic parameters were analyzed using a generalized estimation equation (GEE) model. A total of 510 eyes of 260 healthy subjects were analyzed in the study.

Results:
--The total VD in the optic disc area was 17.21±2.15 mm 1 (95% CI, 17.02–17.40mm 1).

--The VD in the inner ring and the outer ring of the optic disc were significantly higher compared with the central ring, while the VD of the superior quadrant and inferior quadrant was significantly higher compared with the temporal and nasal quadrant.

--After adjusting for the ocular factors and systemic factors, AL (beta =-0.4917), disc area (beta =-0.3748), CMT (beta =-0.0183) and SSI (beta -=1.0588) were significantly associated with total VD of the optic disc.

In healthy subjects, the mean total VD in the optic disc region was 17.21 2.15 mm 1, with superior and inferior VD being substantially higher than temporal and nasal VD. AL, disc area, CMT, and SSI can all influence total VD in the optic disc area and should be taken into account in clinical practice.

Source: https://bmcophthalmol.biomedcentral.com/articles/10.1186/s12886-021-01896-5
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