Radiation-Induced Malignancies: Our Experiences With Five Ca
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Case
A 65-year-old male presented in January 2002 with lump in right breast for 2 months. He was diagnosed with carcinoma breast, was operated and received six cycles of adjuvant chemotherapy with cyclophosphamide, adriamycin, 5-flurouracil (CAF) and external beam radiotherapy (50 Gy in 25 fractions) to chest wall, axilla, supraclavicular and internal mammary portals by cobalt 60. Patient was asymptomatic during follow-up. In June 2016, patient presented with complaints of difficulty in swallowing solid and semisolid food. Upper gastrointestinal endoscopy showed an ulcerative growth with luminal narrowing at a distance of about 22 cm from incisor. Biopsy was done and histopathological examination (HPE) revealed moderately differentiated squamous cell carcinoma (MDSCC) (Fig. 1a). Whole body positron emission tomography-contrast-enhanced computed tomography (PET-CECT) revealed fluorodeoxyglucose (FDG) avid mass lesion in esophagus, about 3.5 cm in craniocaudal dimension (Fig. 1b). According to the age and Karnofsky performance score (KPS) 50, patient was planned for palliative radiotherapy to esophagus, but the patient expired before receiving treatment....

http://wjon.org/index.php/wjon/article/view/991/760
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