Rapid Respiratory Virus Testing does not decrease Antibiotic
A Study was conducted to determine whether RRP testing leads to decreased antibiotic use and health care use among children with influenzalike illness (ILI) in an ED.

A randomized clinical trial among children aged 1 month to 18 years presenting to an ED with ILI was conducted. All children received a nasopharyngeal swab for RRP testing and were randomized 1:1 to the intervention group or control group. Results were available in 45 minutes.

--Among 931 ED visits, a total of 795 RRP test results were positive. The median age of the children was 2.1 years; 509 were boys.

--Most children had a high-risk medical condition. In the intention-to-treat intervention group, children were more likely to receive antibiotics, with no significant differences in antiviral prescribing, medical visits, and hospitalization.

--In inverse propensity-weighted modified intention-to-treat analyses, children with test results known were more likely to receive antivirals (RR, 2.6) and be hospitalized (RR, 1.8); there was no significant difference in antibiotic prescribing (RR, 1.1).

Conclusively, the use of RRP testing in the ED for ILI did not decrease antibiotic prescribing in this randomized clinical trial.

Source: https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2780599