Recovery of Contrast Sensitivity After Descemet Membrane End
A study was conducted to analyse the change in contrast sensitivities in eyes with Fuchs endothelial dystrophy and bullous keratopathy after Descemet membrane endothelial keratoplasty (DMEK).

50 pseudophakic eyes of 50 patients who received DMEK surgery were included. Visual acuity; contrast sensitivity using OPTEC 6500 at spatial frequencies of 1.5, 3, 6, 12, and 18 cycles/degree in photopic and mesopic light with and without glare; central corneal thickness (CCT); and anterior and posterior corneal aberrations were measured preoperatively and at 3 and 12 months postoperatively.

--Best-corrected visual acuity and photopic and mesopic contrast sensitivities with and without glare improved significantly, whereas CCT decreased significantly.

--Preoperative CCT correlates significantly with preoperative photopic contrast sensitivity and postoperative total anterior aberrations correlates with postoperative photopic contrast sensitivity.

Conclusively, photopic and mesopic contrast sensitivities are decreased in patients with Fuchs endothelial dystrophy and bullous keratopathy, especially when glare is present. Preoperatively, the degree of corneal thickness appears to have the greatest impact on contrast sensitivity. DMEK surgery greatly enhances contrast sensitivity. Postoperative contrast sensitivities are limited by greater postoperative anterior corneal aberrations.