Recurrent atypical polypoid adenomyoma and pregnancy: A new
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Atypical polypoid adenomyoma (APA) is a rare benign mixed epithelial and mesenchymal tumor. Histologically APA is characterized by a mixture of benign endometrial glands with structural atypia and a prominent cellular, smooth muscle stroma.Although APA is considered a benign disease, it may recur, furthermore it is reported a frequent APA coexistence with endometrioid adenocarcinoma of the endometrium or with atypical endometrial hyperplasia and the possibility of APA progression to endometrioid adenocarcinoma of the endometrium. APA is often diagnosed in childbearing and premenopausal patients, with the reported median age of 40 yearss. In post-menopause hysterectomy is the treatment of choice, while in patients who may want to preserve the fertility potential a conservative surgical procedure has been suggested.We report the case of a patient who experienced 2 recurrences of APA after conservative hysteroscopic resections, submitted to hormonal treatment with levonorgestrel releasing intrauterine system for 12 months. Afterwards she was referred to Fertility Center and conceived after induction of ovulation with clomiphene. She delivered a baby boy by caesarian section....

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524299/
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