Regeneration of mandibular ameloblastoma defect with the hel
Now open: Certificate Course in Management of Covid-19 by Govt. Of Gujarat and PlexusMDKnow more...Now open: Certificate Course in Management of Covid-19 by Govt. Of Gujarat and PlexusMDKnow more...
Ameloblastoma is a benign odontogenic tumor, which is locally aggressive in behavior. Till date, the treatment of choice is resection and reconstruction using a variety of modalities. Inadequate resection may lead to many complications such as bone deformity and dysfunction.

This report is about a 14-year-old male with ameloblastoma treated with autologous dental pulp stem cells (DPSCs) and stromal vascular fraction (SVF) and evidence of bone regeneration. Marsupialization was performed; tooth was extracted and sent for DPSC cultivation. On the day of surgery, SVF was processed from the buccal pad of fat, and platelet-rich fibrin (PRF) was prepared from patient's peripheral blood. During the procedure, labial plate resection and curating of tumor lining were done. After which, a mesh packed with SyboGraft T-plug, prepared SVF, DPSCs, and PRF were placed over lingual cortex and pressure dressing was done. After the 1st month of surgery, the postoperative course was uneventful, the wound shrinkage led to the exposure of mesh in the intraoral region. Removal of exposed mesh was done. The correction surgery with removal of part of the mesh and primary closure was achieved with SyboGraft plug, SVF and PRF. The enhanced bone formation was seen in post-operative OPG and CT Scan after the 10th month.

https://goo.gl/6tbLWq
M●●●●●i S●●●●e and 3 others like this
Like
Comment
Share