Relation of Pterygium Morphology with Loss of Corneal Endoth
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A Study was conducted to determine the difference in mean corneal endothelial cell density (CECD) between the healthy and diseased eyes of the patients with unilateral pterygium with different morphology patterns by using a non-contact specular microscope and to find out any relationship between severity of pterygium and daily sunlight exposure with the CECD loss.

200 eyes (n= 100 patients) of age range18 -68 years with unilateral pterygium were selected. Necessary demographic data and essential variables like age, smoking status, occupation, and daily direct sunlight exposure were determined. The severity of pterygium (grading) based on its morphology was determined by slit-lamp examination. CECD of each patient was carried out using a non-contact Specular Microscope. The healthy eye (without pterygium) of a patient was considered as control.

Results:
--The age range in this study was 18– 68 years, with a mean age of 43.80 ± 24.37 years with a male to female ratio of 1.6:1.

-- The study reported a mean corneal endothelial cell density (CECD) of 2411.61± 143.64 vs 2751.41 ± 123.674 cells/mm2 in diseased and normal eyes, respectively.

--CECD was lower in grade 3 pterygium compared to less severe pterygium { grade 3 (Fleshy) =2261 cells/mm2 vs grade 2 (Intermediate)= 2413 cells/mm2 vs grade 1 (Atrophic)=2459 cells/mm2} although this difference between the groups was not found to be significant.

--No significant association between sunlight exposure and CECD loss was observed.

Conclusively, this study concluded that the mean corneal endothelial cell density in patients with unilateral pterygium using a non-contact specular microscope were 2411.61± 143.64 cells/mm2.

Source: https://www.dovepress.com/is-pterygium-morphology-related-to-loss-of-corneal-endothelial-cells-a-peer-reviewed-article-OPTH
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