Renal function and mortality in patients with atrial fibrill
Out of 1064 hospitalized patients with atrial fibrillation, 465 (43.7%) had comorbid CKD. The presence of CKD was associated with an increased risk for both all-cause and cardiovascular mortality following hospitalization [adjusted hazard ratio (aHR): 1.60; 95% confidence intervals (95% CIs): 1.25–2.05 and aHR: 1.74; 95% CI: 1.30–2.33, respectively]. The aHRS for all-cause mortality in CKD stages 2–5, as compared with CKD stage 1 were 2.18, 2.62, 4.20, and 3.38, respectively (all P < 0.05). In spline curve analyses, eGFR values lower than 50 ml/min/1.73 m2 were independent predictors of higher all-cause and cardiovascular mortality. In recently hospitalized patients with atrial fibrillation, the presence of CKD was independently associated with decreased survival, which was significant across CKD stages 2–5, as compared with CKD stage 1. Values of eGFR lower than 50 ml/min/1.73 m2 were incrementally associated with a worse prognosis.

Source: https://journals.lww.com/jcardiovascularmedicine/Abstract/2022/07000/Renal_function_and_mortality_in_patients_with.3.aspx
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