Repurposed Anti-Protozoal Drug Emetine Effective Against Cov
Now open: Certificate Course in Management of Covid-19 by Govt. Of Gujarat and PlexusMDKnow more...Now open: Certificate Course in Management of Covid-19 by Govt. Of Gujarat and PlexusMDKnow more...
Get authentic, real-time news that helps you fight COVID-19 better.
Install PlexusMD App for doctors. It's free.
Scientists at the Haryana-based National Centre for Veterinary Type Cultures of Indian Council of Agricultural Research (ICAR) have found that emetine, an anti-protozoal drug, can be repurposed to treat Covid-19.

Emetine is an FDA-approved drug which is used to treat amebiasis, a parasitic disease. Besides, it is also used to induce vomiting in the cases of poisoning. A team led by senior scientist Dr Naveen Kumar identified Emetine as one of the candidate drugs.

The scientists discovered that in order to stop synthesizing viral proteins, emetine inhibits binding of a cellular protein required for the initiation of protein translation to the viral mRNA. In conclusion, antiviral efficacy against SARS-CoV-2 in the cell culture suggests that emetine could be repurposed to treat Covid-19.

The scientists also evaluated antiviral efficacy of emetine against infectious bronchitis virus (IBV, also known as chicken coronavirus) where emetine was found to completely protect chicken embryos against lethal challenge with IBV.

"Upon emergence of Covid-19, they evaluated their inhibitor library and identified emetine as one of the candidate drugs against Covid-19." Dr Naveen added.

Source:
https://economictimes.indiatimes.com/industry/healthcare/biotech/healthcare/repurposed-anti-protozoal-drug-emetine-effective-against-covid-indian-scientists/articleshow/79761936.cms
Dr. T●●●●z H●●●●●●i and 5 others like this2 shares
Like
Comment
Share