Resilience Through Squamous Cell Carcinoma and Rhabdomyosarc
Now open: Certificate Course in Management of Covid-19 by Govt. Of Gujarat and PlexusMDKnow more...Now open: Certificate Course in Management of Covid-19 by Govt. Of Gujarat and PlexusMDKnow more...
Introduction
Among the malignant oral cavity lesions, squamous cell carcinoma comprises the most common pathologic type, associated with significant morbidity, speech and swallowing disabilities. Despite recent diagnostic and therapeutic improvement, a 10% increase in mortality is observed in the last 5 years. The increased mortality related to squamous cell carcinoma of tongue (SCCOT) is perhaps due to the fact that most cases (94.3%) present with locally invasive disease, with incidence rate highest amidst fourth and sixth decades of life.

Rhabdomyosarcoma (RMS) is a malignant soft tissue lesion occurring most frequently in children in the initial decades, with 250 new cases diagnosed in the United States per annum. However, it is a rare entity in adults and carries an adverse prognosis, possibly due to differences in histological subtypes, lack of treatment protocols and presentation in advanced stages.

This case elaborates long-term survival and management of a middle-aged man with a history of SCCOT. It was followed by a complete cure, with further development of spindle cell rhabdomyosarcoma (SC-RMS) of the oral cavity as a metachronous primary lesion. The depth of invasion, en block tumor resection and involvement of regional lymph nodes are the major dynamics to evaluate for prognosis and recurrence rate. Our case is unique because of its peculiar age of presentation of 30 years, along with its favorable survival of 8 years....

http://wjon.org/index.php/wjon/article/view/978/745
Dr. A●●●●●a G●●●a and 2 other likes this
Like
Comment
Share