Response to sunitinib (Sutent) in chemotherapy refractory cl
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Clear cell ovarian cancer (OCCA) is an uncommon subtype of epithelial ovarian cancer accounting for less than 10% of clinical cases in most reported cohorts. Whereas the precursor cell of the more common high grade serous ovarian (HGS) cancer has been hypothesised to be secretory epithelium of the distal fallopian tube the precursor of clear cell ovarian cancer is less clear. The recent association of clear cell histology with previous areas of endometriosis has pointed towards an entirely different cell of origin and indeed molecular characterisation has confirmed this fundamental disparity between HGS and OCCA. This report illustrates a response to sunitinib in a patient with parenchymal hepatic deposits and chemotherapy refractory OCCA.

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