Retinochoroidal toxoplasmosis in a patient with cerebral pos
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Toxoplasmosis is a relatively rare complication in renal transplant patients and can pose diagnostic challenges, especially when it manifests as an ocular inflammation. Authors hereby report an unusual case of a 57-year-old male who developed retinochoroidal toxoplasmosis after 15 years of renal transplant, the diagnoses of which were challenging as the patient was also a known case of cerebral post-transplant lymphoproliferative disease (PTLD) of Hodgkin’s type, which misled the ophthalmologists towards a clinical diagnosis of ocular PTLD. Histopathology examination of the enucleated eye revealed numerous toxoplasmosis cysts within the retina and choroid. No ocular PTLD was observed.

Case description
A 57-year-old male presented to Aachen University Eye Clinic in June 2009 with bilateral uveitis and vitritis. He had undergone a renal transplant for chronic glomerulopathy in 1990 and had received immunosuppression with cyclosporin A, mycophenolate mofetil and fortecortin. He suffered episodic uveitis in the left (OS) and right (OD) eyes in 2003 and 2006, respectively (Fig. 1). On both occasions, vitreous biopsies did not reveal definitive infectious causes (e.g. viral or protozoa) in either real time-polymerase chain reaction (RT-PCR) analyses or in bacterial and fungal cultures.

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