Retinopathy Risk Increases in T2DM After Cataract Surgery- A
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The association between cataract surgery and risk of DR is still not well understood, and there have been no prior population-based reports in this area. This study aimed to assess the risk of developing DR after cataract surgery among individuals with type 2 diabetes.

A population-based prospective cohort study was conducted among participants recruited from the Singapore Epidemiology of Eye Diseases Study. Cataract surgery performed before a follow-up visit, determined based on slitlamp evaluation of lens status at baseline and follow-up visits was assessed.

Results A total of 1734 eyes from 972 participants with diabetes were included in the analysis. A total of 163 study eyes had already undergone cataract surgery at baseline, and a total of 187 eyes underwent cataract surgery any time during the follow-up period. Of these 350 eyes, 77 developed DR. Among the 1384 eyes that never underwent cataract surgery, 195 developed DR. After adjustments for age, sex, race/ethnicity, baseline hemoglobin A1c level, duration of diabetes, random blood glucose level, antidiabetic medication use, hypertension, body mass index, and smoking status, multivariable regression analysis showed that any prior cataract surgery was associated with incidence of DR. Subgroup analyses by race/ethnicity showed similar associations in both Malay individuals and Indian individuals.

Conclusively, The findings of this population-based cohort study suggest that prior cataract surgery was associated with a higher risk of developing DR among individuals with diabetes. Further validation is warranted to confirm this association.