Retroperitoneal nongestational choriocarcinoma in a 25-year-
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Introduction
Choriocarcinoma is the most malignant tumor type among gestational trophoblastic diseases. It is characterized by the production of human chorionic gonadotropin (hCG) and is usually intrauterine and gestational. Nongestational choriocarcinoma is very rare, and diagnosis is difficult especially in patients of reproductive age. Hematogenous metastasis develops in early stages of the disease. The most commonly involved sites are the lungs (80%), vagina (30%), pelvis (20%), liver (10%), and the brain (10%). The retroperitoneal space is an exceptional location. We report a case of retroperitoneal nongestational choriocarcinoma in a 25-year-old woman with negative hCG tests. Our report may provide informative data for the diagnosis and treatment of this rare disease.

Case report
A 25-year-old woman, nulligravida, presented to the emergency department complaining of left lower abdominal pain, fever, vomiting, and nausea that had persisted for two days. She had regular menstrual cycles and her last menstrual period was one week prior to presentation. She was using an intrauterine contraceptive device. Urine hCG tests were negative....

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245352/
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