Risk for Acute MI After Ophthalmologic Procedures
Patients 40 years of age from the Norwegian Patient Registry (2008–2014) and Swedish National Patient Registry (2001–2014) who suffered first-time AMI were included in the study cohort if at any time during the 0- to 7-day interval prior to AMI (defined as the hazard period) or the 29- to 36-day interval prior to AMI (defined as the control period), that subject underwent ophthalmologic surgery. Using a case-crossover study design, the authors compared incidence of AMI during the hazard versus control periods, postulating that any increase in AMI risk relatable to surgery would manifest within the 7 postoperative days. Procedures were stratified by complexity and duration, and patients were categorized as low versus high risk based on presence or absence of documented medical comorbidities during the 2-year period preceding AMI.

Among the 806 patients meeting criteria for inclusion, AMI occurred during the hazard period in 344 subjects and during the control period in 462 subjects, indicating decreased risk of AMI during the hazard versus control period (odds ratio, 0.83; 95% confidence interval, 0.75- 0.91). No clear increase in relative risk was observed during the hazard period based on procedural duration, patient complexity, or use of general versus local anesthesia. However, the majority of cases were <20 minutes in length, were classified as low–intermediate complexitiy, and utilized general versus local anesthesia. The majority of patients were >65 years of age, and were considered low risk in terms of comorbidities.

Short-term risk of AMI was lower in the 7-day time period immediately following ophthalmologic surgery compared to a 7-day period in the more distant future, between 29–36 days after ophthalmologic surgery. The impact of subpopulation effects cannot be excluded due to low representation of patients with high comorbidity burden and procedures lasting >20 minutes.

Source: https://www.acc.org/Latest-in-Cardiology/Journal-Scans/2022/03/29/17/42/Risk-for-Acute-Myocardial-Infarction
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