Risk of Acquired Morbidity in Survivors of Pediatric Acute R
Acquired morbidity in the respiratory and feeding domains was prevalent in (PARDS) survivors. Functional results of survivors have been increased with increased mortality rates in the pediatric acute respiratory distress syndrome (PARDS). Researchers are concerned with describing a change in the FSS from baseline to discharge and identifying risk factors that are linked to poor functional outcomes.

Clinical records of patients with PARDS were examined. The primary outcome was acquired morbidity at PICU and hospital discharge (defined by an increase in FSS more than 3 points above baseline). Severity of illness scores and severity of PARDS were included in bivariate analysis for risk factors for acquired morbidity.

--There were 181 patients with PARDS, of which 90 survived. Median pediatric index of mortality 2 score was 4.05 and 21 survivors had severe PARDS.

--59 and 14 patients had acquired morbidity at PICU and hospital discharge, respectively.

--Median baseline FSS was 6.00, which increased to 11.00 at PICU discharge before decreasing to 7.50 at hospital discharge.

--All patients had significantly higher FSS at both PICU and hospital discharge median compared to baseline. Feeding and respiratory were the most affected domains.

--After adjusting for severity of illness, severity categories of PARDS was not a risk factor for acquired morbidity.

Finally, in PARDS survivors, acquired morbidity in the respiratory and feeding domains was prevalent. These two domains of functional outcomes in these children should be given special attention.

Source: https://onlinelibrary.wiley.com/doi/10.1002/ppul.25520?af=R