Risk of Secondary COVID-19 Transmission Low in Most Settings
Now open: Certificate Course in Management of Covid-19 by Govt. Of Gujarat and PlexusMDKnow more...Now open: Certificate Course in Management of Covid-19 by Govt. Of Gujarat and PlexusMDKnow more...
Get authentic, real-time news that helps you fight COVID-19 better.
Install PlexusMD App for doctors. It's free.
The risk of secondary transmission is less than 4% overall among close contacts of people diagnosed with COVID-19 and varies by settings and disease severity, new research shows.

This Prospective cohort study aimed to evaluate the risk for transmission of SARS-CoV-2 to close contacts in different settings.

3410 close contacts of 391 index cases were traced. Data on the setting of the exposure, reverse transcriptase polymerase chain reaction testing, and clinical characteristics of index and secondary cases were collected.

Results:
-- Among 3410 close contacts, 127 were secondarily infected.
-- Of these 127 persons, 8 were asymptomatic.
-- Of the 119 symptomatic cases, 20 were defined as mild, 87 as moderate, and 12 as severe or critical.
-- Compared with the household setting (10.3%), the secondary attack rate was lower for exposures in healthcare settings and on public transportation.
-- The secondary attack rate increased with the severity of index cases, from 0.3% for asymptomatic to 3.3% for mild, 5.6% for moderate, and 6.2% for severe or critical cases.
-- Index cases with expectoration were associated with higher risk for secondary infection (13.6% vs. 3.0% for index cases without expectoration).

Conclusively, Household contact was the main setting for transmission of SARS-CoV-2, and the risk for transmission of SARS-CoV-2 among close contacts increased with the severity of index cases.

Source: https://www.acpjournals.org/doi/10.7326/M20-2671
K●●●●●a M●●●●●●●●i and 8 others like this3 shares
Like
Comment
Share